Morris was selected as the 41st pick in the 2011 NBA draft by the Los Angeles Lakers and played the point guard position.

Prior to attending Michigan, Morris led Windward School to the 2009 California state championship while earning the California Interscholastic Federation (CIF) Division 5A State John Wooden High School Player of the Year Award.

The National Association of Basketball Coaches named him as a 2nd team All-District selection for the district composed of Big Ten schools.

[2] As a brash freshman, Morris promised the media that he would be able to dunk and lead Windward to a state championship before he graduated.

[1] As a senior, Morris led Windward High School to the California Division V state title, posting a game-high 25 points, eight rebounds and four assists in the championship game.

[9] On November 14, Morris began the season for #15 ranked Wolverines in the starting lineup, posting 11 points and 5 assists against Northern Michigan.

[20] Morris established a new Michigan single-season assists record during the 2011 NCAA Division I men's basketball tournament (235 in 35 games).

[28] Following the season, Morris sought the advice of the NBA's undergraduate advisory committee to determine his draft prospects.

[29] On May 4, Morris announced his final decision not to withdraw his name prior to the May 8 deadline and to enter the June 23, 2011, NBA draft.

[30][31][32] ESPN's Chad Ford described Morris at 6 feet 5 inches (1.96 m) as the biggest true point guard in the draft.

[38] Morris began seeing action as Blake endured a costrochaondral fracture of the cartilage that connects the rib to the sternum in subsequent games.

[39] Morris stayed in the main rotation for seven games during Blake's rib injury before returning to a limited role.

[47] On November 9, 2012, Darius Morris recorded 10 points, a career-high 5 rebounds, 5 assists, and 1 steal in a 101–77 Lakers win over the Golden State, backing up Blake, while Steve Nash was injured.

[48] On November 13, with both Blake and Nash injured, Morris made his first career start against the San Antonio Spurs.

[54][55] This was part of a common strategy employed by Lakers head coach Mike D'Antoni to play players out of position.

[65] On April 26 in the 2013 NBA playoffs against the San Antonio Spurs, with Bryant, Nash, Blake and Meeks sidelined,[66] Morris had his best day as a pro,[67] tallying 24 points and 6 assists in a starting role.

[71] As the September 28 training camp date approached, Morris was expected to battle with Tony Wroten for the backup point guard position behind Michael Carter-Williams.

[73] On November 16, 2013, he scored an NBA regular season career-high 20 points along with 2 assists in a 135–98 loss to the New Orleans Pelicans.

[79] On January 6, 2014, Morris signed a 10-day contract with the Los Angeles Clippers after Chris Paul suffered a separated shoulder.

[87] Mike Conley Jr. had been injured and Jerryd Bayless had been recently traded, leaving the team short at point guard.

[105] That night, he made his season debut in a 118–97 win over the Oklahoma City Blue, recording nine points, three rebounds, four assists and two steals in 24 minutes off the bench.

[107] On January 5, 2018, Morris was conditionally signed by Guangdong Southern Tigers of the Chinese Basketball Association (CBA) to replace Edwin Jackson.

[108] On February 21, 2018, he did not renew his contract with the Guangdong Southern Tigers after the team signed Donald Sloan as the replacement.