During his National Basketball Association (NBA) career, he also played for the Cleveland Cavaliers, Memphis Grizzlies, Phoenix Suns and Detroit Pistons.

[1] One scouting report read: "At 6-foot-10, 228-pounds, Leuer definitely needs some time to fill out his frame for high-major competition.

[5] Leuer had originally entered high school as a guard, but had a 10-inch growth spurt before his senior year.

The most points he scored during the non-conference season was 12, but he exploded for 25 (on 8 of 9 shooting) against the Michigan Wolverines in the Big Ten opener.

He had 13 double digit scoring games including 17 in a victory at Virginia Tech in the ACC-Big Ten Challenge.

[9] On December 2, 2009, in a game on ESPN, Wisconsin shocked the #5 Duke Blue Devils (who would be the eventual National Champions).

[10] Leuer poured in 17 points on his way to scoring double digits in 13 of the first 15 games of the year.

However, Leuer would score double digits in each of the final five games of the year, including 20 against the University of Illinois, as the Badgers went 4–1 down the stretch and finished 13–5 in the Big Ten, good enough for fourth place and a #13 national ranking.

Leuer went with the team to New York City to compete against the likes of Kobe Bryant, LeBron James, and Dwyane Wade.

During the first half of the game, Leuer became the 36th player in Wisconsin Badgers history to score 1,000 points in a career.

[28] On January 22, 2013, Leuer was traded to the Memphis Grizzlies in exchange for Marreese Speights, Wayne Ellington, Josh Selby, and a future first-round draft pick.

[30][31] On December 3, Leuer recorded a career-high 23 points, along with 9 rebounds and 3 blocks, in a 110–91 win over the Phoenix Suns.

Six days later, he recorded his first career double-double with 16 points and a career-high 12 rebounds in a 94–85 win over the Orlando Magic.

[32] On December 7, 2014, Leuer had a season-best game with 20 points and career-high tying 12 rebounds in a 103–87 win over the Miami Heat.

[33] On June 25, 2015, Leuer was traded to the Phoenix Suns in exchange for the draft rights to Andrew Harrison.

[34] He made his debut for the Suns in the team's season opener against the Dallas Mavericks on October 28, recording 14 points and 7 rebounds off the bench in a 111–95 loss.

[38] On March 21, 2016, Leuer recorded his seventh double-double of the season (ninth of his career)[39] with 13 points and 13 rebounds in a loss to his former team, the Memphis Grizzlies.

Two days later, he had 22 points and a career-high 14 rebounds in a 119–107 win over the Los Angeles Lakers,[40] recording back-to-back double-doubles for the first time in his career.

[41] In the Suns' season finale on April 13, Leuer recorded 16 points and matched his career best with 14 rebounds in a 114–105 win over the Los Angeles Clippers.

[45] Leuer played in only eight games during the 2017–18 season due to an ankle injury, and he decided to have season-ending surgery on it in January.