DeLeón is produced in the town of Purísima del Rincón in the Mexican state of Guanajuato.

The brand was founded by Brent Hocking in 2008 and purchased in 2013 by Sean "Puff Daddy" Combs and the beverages giant Diageo as equal ownership partners.

[5][6] In December 2013 it was announced that Sean "Puff Daddy" Combs would become a partner of DeLeón Tequila following the success of his work with the Cîroc vodka brand.

[7] A few weeks later it emerged that Combs had in fact co-purchased DeLeón Tequila in partnership with Diageo, with whom he had worked with on growing Cîroc.

In 2024, following a legal dispute, Combs ceased to be associated with the Diageo joint venture which owned DeLeón and Cîroc.