The Blue Demons play home games at Wintrust Arena at the McCormick Place convention center on Chicago's Near South Side.

Meyer led DePaul past Bowling Green to capture the 1945 National Invitation Tournament, the school's only post-season title.

During Ray Meyer's tenure, the Blue Demons originally played in University Auditorium before moving to Alumni Hall in 1956.

For the start of the 1980 season, DePaul men's basketball moved to the Rosemont Horizon later renamed Allstate Arena.

In 1992, the Blue Demons were co-champions of the newly formed Great Midwest Conference but made their last NCAA tournament appearance under Meyer.

[12] It was the first time a member of the Meyer family hadn't coached DePaul basketball in 55 years.

In his second season, his team advanced to the second round of the 2004 NCAA tournament before being eliminated by eventual national champion Connecticut.

In his second season in 2006–07, the Blue Demons beat #5 Kansas, pulling off one of the greatest upsets in school history.

Four games into the 2007–08 season, Wainwright logged his 200th career win as a head coach, but the team finished with a 10–19 record.

On April 6, 2010, Oliver Purnell, formerly of Clemson University signed a seven-year deal with DePaul.

For the 2017–2018 season, the Blue Demons moved back to Chicago to play their home games at 10,387-seat Wintrust Arena at the McCormick Place convention center.

Following the 2017–2018 season, DePaul's eleventh straight losing season under coaches hired by current Athletic Director Jean Lenti Ponsetto, a group of "concerned students and alumni" purchased a full-page advertisement in the Chicago Sun-Times calling for change within the school's Athletic Department.

In Leitao's fourth season, he led the Blue Demons to the 2019 College Basketball Invitational post-season tournament.

Holtmann and the 2024–25 team went 7-1 to start the season, losing their first game on the road to Texas Tech on December 4, 2024.

Shutting out Georgetown at the Capital One Arena 73―68, their first conference win in 1 year and 364 days after 39 straight losses.

DePaul has played in two Final Fours in the NCAA Division I men's basketball tournament.

DePaul has won a total of two conference championships since leaving independent status following the 1990–91 season.

* Vacated by the NCAA The Blue Demons have appeared in the National Invitation Tournament (NIT) 16 times.

[25] The following former DePaul Blue Demons have played in the NBA or original ABA:[26] The following former DePaul Blue Demons have played professionally in leagues outside of the United States: Wintrust Arena is a 10,387-seat multi-purpose sports venue in Chicago.

The arena opened in 2017 and is home of the DePaul Blue Demons men's basketball team.

Alumni Hall was completed in 1956 and was the on-campus home venue of the DePaul Blue Demons men's basketball team through 1980 when the Rosemont Horizon opened.

[29] University Auditorium, nicknamed "The Barn", was the original on-campus home gymnasium for DePaul men's basketball starting in 1923 until 1956.

[29] McGrath-Phillips Arena, located in the Sullivan Athletic Center, was the home venue for select on-campus games for the men's basketball team from 2000 until 2017.

[29] McGrath-Phillips Arena is the practice facility for the DePaul Blue Demons men's basketball team.