Part of this property was donated by the family of the late National Artist for Architecture Leandro Locsin (DLSU HS 1947).

The Brothers of the Christian Schools, officially known as Fratres Scholarum Christianarum or FSC, is a congregation dedicated to the teachings espoused by Saint Jean Baptiste de La Salle.

Unable to accommodate requests for admission to the elementary grades, they had to revert an earlier policy not to expand.

They have also undertaken supervision of some schools in Manila, Cavite, Bataan, Cebu, Bukidnon, Surigao del Sur, Negros Occidental, Masbate, Capiz, and Ozamis.

Hence, De La Salle Canlubang (DLSC) was established in June 2003 in order to address the educational concerns of our nation with its youth as its strength.

They are envisioned to be grounded on science and technological skills cloaked in the ideals of St. La Salle as an answer to the demands and challenges of the 21st century.

After DLSC was integrated into DLSU to become De La Salle University Science and Technology Complex (DLSU -STC) in 2012, its Integrated School has grown to be one of the most progressive educational institutions south of Metro Manila with a population of more than 1,000 students from Kinder 1 to Grade 12 geared towards producing lifelong learners with the spirit of Faith, Service and Communion and equipped to meet the challenges of the new 2000 millennium.

Beginning construction in August 2005, the Integrated School building was finished in March 2006, right on time for the following academic year.