A later waqf named the revenues of Deir al-Ghusun and a mosque (masjid), tomb (turba) (presently Khalidi Library), to be given for "the cure of the sick and the preparing of the dead for burial in Jerusalem.

"[5] Deir el-Ghusun may have been the village marked as "El Dair" on Pierre Jacotin's map surveyed during Napoleon's 1799 invasion during the late Ottoman period.

[7] During the 1834 Peasants' revolt in Palestine, Ibrahim Pasha of Egypt pursued rebels to nearby Zeita.

[8] At Deir al-Ghusun, many of the inhabitants and rebels heeded a call by Husayn Abd al-Hadi to flee once the Egyptian troops arrived.

[9] Ibrahim Pasha's troops stormed the hill at Deir al-Ghusun and the rebels (mostly members of the Qasim, Jarrar, Jayyusi and Barqawi families) were routed, suffering 300 fatalities.

[8] In 1852, Edward Robinson noted: "From 'Attil we now turned again up the mountain, following the direct road to Nabulus; and taking a guide for Ramin.

Leaving the village at 11:15, we descended into the southern basin, and then entered a long shallow valley running up on the right of Deir el-Ghusun and its hill.

[13] In the early 20th century, residents of Deir el-Ghusun established agricultural hamlets known as khirba, used mainly during the plowing and harvesting seasons, on the outskirts of the village.

[16] In the 1945 statistics, Deir al-Ghusun was counted with the villages which later made up Zemer, and together they had a population of 2,860 Muslims,[17] with a total of 27,770 dunums of land.

[22] Since the establishment of the Palestinian National Authority in 1994, the built-up area of the town increased by over 20% or an annual expansion of 34 dunams by 2000.

[22] Deir al-Ghusun was more prosperous than other Palestinian towns, however, the confiscation of substantial amounts of cultivable land east of the Green Line, the temporary sanctions against the Palestinian National Authority in 2006-2007, and the disruption of trade and transportation by Israeli West Bank Barrier has somewhat hampered the economy.

[27] Approximately 53% of Deir al-Ghusun's residents are within the employment age range (15-64) and females constitute a significant 48% of the local labor force.