It can be isolated from stressed grapevine (Vitis vinifera) leaves.

[3] It is also found in plant cell cultures[4] and wine.

[1] It is a grapevine phytoalexin following stresses[3] like fungal infection (by Plasmopara viticola, the agent of downy mildew),[6] UV light irradiation or ozone treatment.

[7] Botryosphaeria obtusa, a pathogen responsible for the black dead arm disease of grapevine, has also been shown to be able to oxidise wood δ-resveratrol into delta-viniferin.

[9] Delta-viniferin can also be produced from resveratrol by human PTGS1 (COX-1, cyclooxygenase-1)[10] or from trans-resveratrol and (−)-epsilon-viniferin by horseradish peroxidase.