The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.

This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.

Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.

This protein may be involved in both male gonadal differentiation and perineurial development.

[7] This article incorporates text from the United States National Library of Medicine, which is in the public domain.