is an open world action-adventure video game franchise that is designed as a parody of Cold War-era alien invasion films.

Grant Albrecht and Richard Steven Horvitz, with the exception of the game Big Willy Unleashed, in which actors Sean Donnellan and Darryl Kurylo portray the characters.

In Destroy All Humans!, Crypto's objectives also include investigating what happened to his previous clone.

2 features Crypto hunting for revenge, after the KGB try to assassinate him and successfully destroy the mothership and his mission officer, Orthopox-13 (Pox), as well as exterminating the Furons' enemy from the Martian War, the Blisk.

Pox sends Crypto on a mission to harvest human brain stems (which contain a small amount of pure Furon DNA due to an encounter between Furon warriors and humans in ancient times) to prevent his species from going extinct.

To accomplish his mission, he must fight and defeat the Majestic agency, a shadowy government organization led by a black-clad figure named Silhouette.

Pox has downloaded his consciousness into a personal holographic projector designed to communicate between Furons on Motherships and planet surfaces.

Using the money earned from the Big Willy fast food franchise that Orthopox started in Big Willy Unleashed, Pox and his destructive Furon warrior minion Crypto have opened a casino which they use to obtain a steady financial income and human DNA.

Crypto has lost his motivation because of the death of Natalya (which was a clone with a four-year lifespan) and has forgotten what it means to destroy humans.

Soon Crypto finds himself face-to-face with a conspiracy from his own homeworld that, if not stopped, could destroy his entire race.

In the midst of all the chaos, Crypto hears a voice in his head, telling him to go to the city of Shen Long.

Later, Crypto, while in Sunnywood, is shot in the neck, faints, and then wakes up in a Kung Fu monastery where he is greeted by a Furon martial arts expert known as The Master.

The remake was developed by Black Forest Games and released on July 28, 2020, for Microsoft Windows, PlayStation 4, Xbox One, on December 8, 2020, for Stadia, and on June 29, 2021, for Nintendo Switch.

Clone Carnage, was released for Microsoft Windows (via Steam, Epic Games Store and GOG.com), PlayStation 4, and Xbox One on May 31, 2022.