Diamphotoxin is a toxin produced by larvae and pupae of the beetle genus Diamphidia.
Diamphotoxin is a hemolytic, cardiotoxic, and highly labile single-chain polypeptide bound to a protein that protects it from deactivation.
[5] The San people of Southern Africa use diamphotoxin as an arrow poison for hunting game.
Large mammals hunted in this way die slowly from a small injection of the poison.
[6] Several leaf beetles species of genus Leptinotarsa produce a similar toxin, leptinotarsin.