Frequent physical effects are nausea, numbness of the tongue or throat, and pupil dilation.

[10] While dipropyltryptamine is chemically similar to dimethyltryptamine (DMT), its psychoactive effects are markedly different.

[11] Negative side effects of human consumption of this drug may include increased heart rate, dizziness, anxiety, panic, confusion, paranoia, delusions, seizure (uncommon) and nausea.

DPT is used as a religious sacrament by the Temple of the True Inner Light, a New York City offshoot of the Native American Church.

[13] DPT is a Class A drug in the United Kingdom, making it illegal to possess or distribute.