Formed in 1925, the company primarily engages in telecommunications and information technology infrastructure.

[3][4] During the 2000s, the company (which subsequently renamed as ISM Communications Corporation in April 2002[4]) began diversified with the investments in different industry sectors[3] such as telecommunications (a stake in Eastern Telecommunications Philippines, later divested in 2011),[5] gaming and hospitality (a 65% stake in Acentic GmbH),[6] and banking (a 97% stake in Philippine Bank of Communications, sold to Lucio Co),[7] before it became a holding company in 2016.

[3] In August 2018, businessman Dennis Uy bought a 45% controlling stake in ISM,[3] and in March 2020, the firm was renamed as Dito CME Holdings Corporation.

The deal made Udenna Corporation became as a parent company of Dito CME.

[10] In January 2022, Dito CME dropped the Rights offering of US$156 million for the expansion in Philippines citing the reason of "less than ideal market conditions.