His Master's thesis was on "Resolution of territorial disputes in international law" where as an example he took the public political claims of some Russian top politicians on the Crimean peninsula and the city of Sevastopil in particular.

[8] While a student at Taras Shevchenko National University of Kyiv, he started his legal career in leading Ukrainian and international law firms.

After finishing his master's degree he moved to "Ilyashev and Partners" law firm, where he specialized in international investments, banking and finance, as well as litigation.

[16] Despite his image of a right-wing nationalist interventionist policy-maker, the Obozrevatel magazine named Natalukha as one of "Top 10 of people who heavily influence the economic policies in Ukraine" in 2021.

He is the chairman and co-founder of the "Ardea Alba" Alumni Club of the Taras Shevchenko National University of Kyiv International Relations Institute.

The Club organizes alumni meetings and other events with notable graduates that include Mikheil Saakashvili, Borys Tarasyuk, Volodymyr Ohryzko and others.

Natalukha is also the founder of the Ukrainian Institute on Territory Branding, a non-governmental organization designed to reinvent the global image of Ukraine as a country.