Dodecamethylcyclohexasilane is the organosilicon compound with the formula Si6(CH3)12.

It is one of the more readily prepared and easily handled polysilanes.

Dodecamethylcyclohexasilane is produced by reduction of dimethyldichlorosilane with sodium-potassium alloy:[1] where M is Na or K. The reaction also produces a polymer poly(dimethylsilylene) [−Si(CH3)2−]n and a cyclic compound decamethylcyclopentasilane Si5(CH3)10.

The chair conformer of dodecamethylcyclohexasilane was confirmed by X-ray crystallography.

[2][3] Dodecamethylcyclohexasilane reacts with potassium tert-butoxide to give the potassium derivative:[4]