[citation needed] Dorje Youdon, Gyari's mother, also the wife of a chieftain, led the Tibetan army into many battles at the age of 18.

[citation needed] Her brother, the late Lodi Gyari Rinpoche, the envoy of the Dalai Lama, and chairperson of International Campaign for Tibet (ICT), raised the profile of Tibet in the global sphere and for leading the ten rounds of Sino-Tibet dialogues until 2010.

During her time as MP and Deputy Speaker, she was a part of the major transitions the Tibetan democracy adopted, from the drafting of the charter-in-exile to direct election of Kalon Tripa (Head of the Cabinet) by the people, to revisiting Tibetan political approach, connecting with world leaders and people to the devolution of political power by the Dalai Lama.

In 2011, Gyari announced her decision to run for Sikyong of the Central Tibetan Administration, equivalent to the prime minister of a country, but withdrew later.

In 2004, she was appointed by the Dalai Lama to be the Chairperson of the Tibetan Centre for Human Rights and Democracy (TCHRD), taking over from Prof. S. Samdhong Rinpoche.