Located within the Fitzroy River basin, the Don River rises in the Don River State Forest below Black Mountain and flows generally west, then southwest, than west, joined by twelve tributaries.

The river reaches its confluence with the Dawson River north of Baralaba.

The Don River descends 175 metres (574 ft) over its 165-kilometre (103 mi) course.

From source to mouth, the river is crossed by the Burnett Highway and the Leichhardt Highway.

This Queensland river or creek related article is a stub.