Pratt, MacDonald, and Phil Proctor are the only cast members to have been involved in all five films.

Maya Dolittle thinks she doesn't have to spend 7 years in college to be a vet because she can talk to animals.

While taking a walk with Lucky, she helps a cat on a tree by talking to it.

She gets discovered and Tiffany Monaco, a Hollywood star, brings her to L.A. to help her little puppy, who turns out to be a male.

Maya soon finds out the show isn't about helping animals and goes back home to study being a vet.