Drug Metabolism and Disposition is a peer-reviewed scientific journal covering the fields of pharmacology and toxicology.

It was established in 1973 and is published monthly by the American Society for Pharmacology and Experimental Therapeutics.

[1][2] The journal publishes articles on in vitro and in vivo studies of the metabolism, transport, and disposition of drugs and environmental chemicals, including the expression of drug-metabolizing enzymes and their regulation.

The journal was published on behalf of the society by Williams & Wilkins until the end of 1996.

[4] According to the Journal Citation Reports, Drug Metabolism and Disposition received a 2020 impact factor of 3.922.