His mother, Billie Baker Gholson, was an accountant who worked as a part-time opera singer and was the first African-American to graduate from Rudi E. Scheidt School of Music at the University of Memphis.

[10][3] Gholson started making hip hop beats at the age of 12 and scored his first production placement on local radio with Memphis rapper Tela's "Double Dose".

Due to the pressure from his parents to achieve academically, his father advised him that a college degree would open more doors for career advancement, and his mother stressed the importance of financial savvy.

[13] Following his father's advice and by his junior year, Drumma Boy established a name for himself and was quickly becoming the most sought-after producers in Tennessee.

[citation needed] He spent much of his spare time outside of classes on the keyboard and drum machine making hip hop beats in his room.

[17] In between attending classes, he would shop his homemade beats to local Memphis rappers such as Gangsta Boo, as well as travel to Texas to work on musical projects for Scarface and Bun B of UGK.

[18] The cash flow from his music production company was so strong that Gholson pulled $20,000 per month where he eventually realized that he had no reason to stay in college.

[5][20] Within two years of leaving his native city, Drumma Boy had fostered relationships with a number of hip hop groups and rappers such as Outkast, Trick Daddy, Slim Thug, DJ Cash Money, Pastor Troy, and Killer Mike.

[21] In October 2013, Drumma Boy conducted a halftime show during the 2013-2014 season opening of his hometown NBA team, the Memphis Grizzlies.

[27] He was quoted in the January 2010 issue of Rolling Stone surrounding his production work for controversial recording artist Gucci Mane's #1 rap album The State vs. Radric Davis.

[29] In November 2009, Drumma Boy released his music video "Dis Girl" shot by Mr. Boomtown, the first single off his mixtape Welcome II My City, which received millions of hits on Worldstarhiphop.

[31][32][33] Gholson also scores for television and film, most recently working on FOX's hit TV show Empire with Bryshere Gray (Yazz).

Gholson cites hip hop and R&B musicians Dr. Dre, Quincy Jones, Raphael Saadiq and The Funk Brothers as his signature music production inspirations with other musical influences ranging from European classical composers Ludwig van Beethoven, Jean Sibelius, Wolfgang Amadeus Mozart, and Johann Sebastian Bach to American jazz icons Dizzy Gillespie and Miles Davis all the way to hip hop group Three 6 Mafia and Houston rapper, Scarface.

His production techniques bring together a diverse array of genres that originate in hip hop, rock, pop, classical, soul, and R&B.