Dry Creek or Dry Creek Drain is a seasonal stream in South Australia[1] which passes through the Adelaide suburbs of Wynn Vale, Modbury, Walkley Heights and Pooraka.

In season Dry Creek flows from its source near Yatala Vale in the Mount Lofty Ranges to the Barker Inlet of the Gulf St Vincent via a manufactured drain near Globe Derby Park.

The name is likely derived from the indigenous word 'yertalla', which means "water running by the side of a river".

[2] Dry Creek is mostly dry in summer and flows through a deep gully at the rear of the prison with outcrops of exposed pre-Cambrian rocks that were extensively quarried as part of prison activity.

The rock from the quarry was transported to Adelaide via the Stockade railway station (opened in 1857; closed 1961), with the area around the station and quarry being since redeveloped as the Stockade Botanical Park.