Georg August (11 January 1824 – 20 June 1876) was a member of the House of Mecklenburg-Strelitz.

He was born in Neustrelitz as second son of George, Grand Duke of Mecklenburg-Strelitz (1779-1860) and his wife Marie (1796-1880), daughter of Prince Frederick of Hesse-Kassel and Princess Caroline of Nassau-Usingen.

His paternal grandparents were Charles II, Grand Duke of Mecklenburg-Strelitz and Princess Friederike of Hesse-Darmstadt.

On 1860 his elder brother Frederick William succeeded their father as Grand Duke of Mecklenburg-Strelitz.

On 16 February 1851 in St. Petersburg, George August married Grand Duchess Catherine Mikhailovna of Russia (1827-1894), daughter of Grand Duke Michael Pavlovich of Russia and had issue: