Duncan Archibald Graham, CC CBE FRSC (January 8, 1882 – February 18, 1974) was a Canadian physician and academic who held the first position in the British Empire of chair of clinical medicine, established by John Craig Eaton at the University of Toronto in 1919.

He held this position and was chair of the department of medicine and physician-in-chief at the Toronto General Hospital, until 1947.

Born on a farm near Ivan, Ontario, he received a Bachelor of Medicine from the University of Toronto in 1905.

He was an assistant bacteriologist with the Ontario Board of Health before starting his residency in pathology at the Toronto General Hospital.

[1] In 1919, he was appointed to the Sir John and Lady Eaton chair in medicine at the University of Toronto on the recommendation of William Goldie.