The Esso Club is a sports bar in Clemson, South Carolina, that evolved from a 1920s gas station and grocery on Old Greenville Highway, which was at the time the main highway between Atlanta, Georgia and Greenville, South Carolina.

[3] ABC sportscaster Brent Musburger makes it a point to have a beer at the Esso when in town for Clemson football and basketball games.

The authors of South Carolina Off the Beaten Path suggest going to the Esso Club to get tickets to games that are sold out years in advance, rather than the stadium.

The main bar is topped with the original cedar seating from Death Valley, Clemson's football stadium.

Spitoono (or Spittoono in alternating years), a local charity fund-raising music festival organized by a loose confederation of Esso Club regulars operating as the Redneck Performing Arts Association (RPAA), was held in the parking lot from 1981 to 1990 by which time it had outgrown the available space.