East Gaffney is a census-designated place (CDP) in Cherokee County, South Carolina, United States.

U.S. Route 29 is the main road through the community, leading west into Gaffney and northeast 7 miles (11 km) to Blacksburg.

[5] As of the census[4] of 2000, there were 3,349 people, 1,380 households, and 916 families residing in the CDP.

There were 1,563 housing units at an average density of 493.8 per square mile (190.7/km2).

27.8% of all households were made up of individuals, and 9.3% had someone living alone who was 65 years of age or older.