Eastern Indonesia borders the Southern Philippines and Palau in the North, Papua New Guinea in the East, and Northern Australia in the South.

After Denpasar Conference, on 24 December 1946, the State of East Indonesia was formed covering the same area, excluding Western New Guinea, previously included during Malino Conference.

[5][6][7] In Eastern Indonesia, the days are generally dry and sunny from October through March with the warm tropical rain season occurring between May and August; temperatures are typically in the 27 °C (81 °F) to 30 °C (86 °F) range throughout the year.

3,726 m (12,224 ft) 3,478 m (11,411 ft) Seaweed farming has traditionally been a common commercial activity along the coasts of Eastern Indonesia; however, in the 2020s climate change in Indonesia has been causing seaweed farmers in Eastern Indonesia to lose revenue and harvests.

[10] In the consumer shopping industry, Eastern Indonesia experienced a rapid increase in online shopping in the 2020s, with overall transactions in the region doubling from 2020 to 2021; this growth has been led by Indonesian e-commerce company Tokopedia, with the top product types sold in the region being health and beauty, fashion, food and beverage, and electronics.