He was the brother of George Nevill, 5th Baron Bergavenny and the two of them became close to King Henry VIII (their distant cousin) and the Queen, Catherine of Aragon.
[1] Edward Neville was Esquire of the Body, and Sewer Keeper (official overseeing service to Henry VIII's household[a]).
The Nevilles and their cousins the Courtenays supported Catherine of Aragon's marriage and for the Pope's authority in England, which alienated King Henry.
Early in 1538, Henry's chief minister Thomas Cromwell was warned that Edward Neville was secretly trying to obtain the estates of Moatenden Priory, which had been recently dissolved.
A patent was issued to Cromwell confirming his estate, possession and interest in the site of the late priory, of Mottenden, and the manors of Mottenden, Plushenden, Plomford, and Delmynden in Kent; the rectory of Lancing, Sussex, and all tithes thereto belonging; the advowson of the parish church of Lancing and the vicarage of the same church; a saltmarsh in Canwynden alias Derwishop, Essex; and all lands, &c., in the counties of Kent, Sussex, and Essex, late of John Gregory alias John Harietsham, late minister of the Trinitarian priory of Mottenden.