Paleček discovered that nucleic acids could be analysed by electrochemical research, contradicting previous assumptions from the 1950s that DNA molecules were too large to be affected by electrochemistry.

[1] Paleček had a specific interest in the fact that most proteins contain sugar, as he believed that analysis of this could lead to better diagnosis of health and illnesses.

[4][5] In 1960, Paleček discovered that nucleic acids could be analysed through electrochemical research, which allowed him to explore how DNA can be used to diagnose genetic diseases.

[6] His discovery contradicted previous assumptions from the 1950s that DNA molecules were too large to be analysed by electrochemical research.

[2] During his life, Paleček authored over 300 scientific works, making him one of the most respected scientists in the Czech Republic.

His death was announced by fellow scientist Eduard Kejnovsky, who worked as Paleček's public relations officer.