Endothelial lipase

These processes include lipoprotein metabolism, cytokine expression, and lipid composition in cells.

[1] Due to the hydrolysis specificity, endothelial lipase contributes to multiple vital systems within the body.

[2] The anti-Atherosclerosis opportunity through alleviating plaque blockage and prospective ability to raise High-density lipoprotein (HDL) have gained endothelial lipase recognition.

When this novel endothelial lipase was over-expressed in mice, the concentrations of HDL Cholesterol and apolipoprotein A-I in plasma decreased.

[5] The suggested relation to metabolism and vascular disease was attributed to tissue selective expression in endothelial cells.

[1] The addition reaction of the same compound and molecules enhances the resistance to cleavage and limited activity is sustained.

[6] HDL cholesterol provides extreme benefits to the body and is vital in sustaining the fluidity of natural membranes.

[1] In summation, endothelial lipase is said to be a pivotal component in metabolism through high-density lipoprotein hydrolysis.

[8] Plaque is detrimental to vascular heath because it narrows and stiffens the arteries, causing a lack of oxygen-rich blood flow.

Data suggests that endothelial lipase inhibition should increase the plasma HDL, primarily in patients with low HDL-C levels.

[4] Although a functional correlation can be drawn, there is little clinical evidence to provide support to the suggested potential benefits in vascular pathophysiology.