1TE6, 2AKM, 2AKZ, 3UCC, 3UCD, 3UJE, 3UJF, 3UJR, 3UJS, 4ZCW, 4ZA0202613807ENSG00000111674ENSMUSG00000004267P09104Q6FHV6P17183NM_001975NM_013509NM_001302642NM_001355220NP_001966NP_001966.1NP_001289571NP_038537NP_001342149Gamma-enolase, also known as enolase 2 (ENO2) or neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene.

Gamma-enolase is one of the three enolase isoenzymes found in mammals.

A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

[5] Click on genes, proteins and metabolites below to link to respective articles.

NSE is produced by small-cell carcinomas, which are neuroendocrine in origin.