Enoxaparin sodium, sold under the brand name Lovenox among others, is an anticoagulant medication (blood thinner).
[11] It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery.
[9] Uncommon (<1%) Common (>1%) Frequency under investigation The FDA issued a revision to the boxed warning for enoxaparin in October 2013.
[18] It may be necessary to delay anticoagulant dosing in these persons in order to decrease the risk for spinal or epidural hematomas, which can manifest as permanent or long-term paralysis.
[17][19] Enoxaparin binds to and activates antithrombin (a circulating anticoagulant) to form a complex that irreversibly inactivates clotting factor Xa.
[20] It has less activity against factor IIa (thrombin) compared to unfractionated heparin (UFH) due to its low molecular weight.
[24] In March 2017, Enoxaparin BECAT, Laboratorios ROVI (Spain) obtained marketing authorization in twenty six countries in Europe.