His Spatial-Landscape Construction (1919) is quasi-abstract with large flat areas in bold colours, predominantly red, orange, blue and dark green.
But by 1931 he had adopted "cosmic idealism", a biomorphic abstractionism quite different from the works of the previous decade, for example in Pilot of the Infinite (1931) and Biological Apparition (1940).
After studying with Dullio Cambellotti at the Academy of Fine Arts in Rome, he became a leading member of the Futurist Movement as a painter, scenographer and architect.
He had close contacts with the representatives of the European avant-garde art, with the Section d'Or, Dadaism, the Bauhaus, De Stijl, the Abstraction-Création group, with Pablo Picasso, Piet Mondrian, Wassily Kandinsky and Jean Cocteau.
[3] Prampolini's work occupies a place of its own in the European abstract art, characterized by its deep concern for the dynamism and Organicism, which manifests itself in the cosmic visions and dreams of the 1930s and 1940s.