Eosinophilic (Greek suffix -phil-, meaning loves eosin) is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye.
Eosin is an acidic dye for staining cell cytoplasm, collagen, and muscle fibers.
[1][2] Eosinophilic describes the appearance of cells and structures seen in histological sections that take up the staining dye eosin.
[3] Eosin is usually combined with a stain called hematoxylin to produce a hematoxylin- and eosin-stained section (also called an H&E stain, HE or H+E section).
Some structures seen inside cells are described as being eosinophilic; for example, Lewy and Mallory bodies.