Episkopi belongs to the community of Kato Chorio within the municipality of Ierapetra, Lasithi.
It lies north of Ierapetra in the middle of the narrowest part of the island.
The village was established during the Minoan period, probably between 2500 and 2000 BCE.
The municipality covers an area of 36 km², while 15 km² are cultivated with olive trees, most of them irrigated from the Bramianos dam, and the springs of Malavra, Thripti, Kefalovrissi and Kato Horio.
At 1946 A.C. a sarcophagus was found in the village from the Minoan period.