[8][9][10][1] Atypical myopathy is a commonly fatal form of equine rhabdomyolysis caused by the toxin Hypoglycin A (HGA).
[10][3][5] HGA is a naturally-occurring amino acid contained by trees and shrubs of Acer genus.
[6] The toxin affects the functioning of horse’s muscle cells by slowing down or stopping the energy production.
[15] Changes in weather conditions and temperature may contribute to the propensity of being affected, which is the reason why many cases are reported during autumn and spring.
In most cases treatment needs to be started before getting the laboratory test results as the confirmation of diagnosis may take several days.
[9] First symptoms are usually muscular weakness, soreness and stiffness causing problems with walking and breathing.
Symptomatic treatment includes intravenous fluid therapy, supplementation of glucose and insulin as well as administration of carnitine, vitamin E, selenium and riboflavin.