Eudistomin

Eudistomins are β-carboline derivatives, isolated from ascidians (marine tunicates of the family Ascidiacea), like Ritterella sigillinoides,[1] Lissoclinum fragile,[2] or Pseudodistoma aureum.

[3][4] Eudistomin C is a naturally occurring β-carboline derivative which has been found in the Ascidian, Eudistoma Olivaseum.

This produces the RPS14A 40S Ribosomal subunit which confers a resistance against Eudistomin C, preventing protein translation inhibition.

[7] A recent study suggested that this cytotoxicity may allow Eudistomin C to bind to DNA molecules.

In addition to this, Eudistomin C displayed antibacterial property in Gram-Positive Bacteria.