Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.

This gene encodes a ribosomal protein that is a component of the 40S subunit.

As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor.

This article on a gene on human chromosome 5 is a stub.