He received a Bachelor of Science degree in Mechanical Engineering-Applied Physics from Columbia University in 1972.

He conducted experimental and theoretical research in fluid dynamics, fundamental materials science, and levitation technology for 20 years.

He performed hands-on experimental investigations in laboratories aboard the NASA KC-135 aircraft, and on the Space Shuttle Columbia.

[4] Trinh was a payload specialist crew member on the STS-50/United States Microgravity Lab-1 Space Shuttle flight in 1992.

[4] As director of the physical sciences research division at NASA, Trinh leads the effort to develop an innovative peer-reviewed scientific program focusing on the effects of gravity on physical, chemical, and biological systems.