[1] In 1930 he became professor at Clinical Infectious and Tropical Diseases (in Portuguese: Clínica de Doenças Tropicais e Infecciosas) at the Faculty of Medicine of Rio de Janeiro, whose discipline was taught by his father, Carlos Chagas.

To fill the vacancy, he defended as a thesis the cardiac form of American trypanosomiasis.

In 1931 he held the position of Human Pathology Section (in Portuguese: Seção de Patologia Humana) of the Instituto Oswaldo Cruz and, in 1935, represented the institution at the Ninth Meeting of the Argentine Society of Pathology North Regional, held in the city of Mendoza to honor the memory of Carlos Chagas, newly deceased.

Upon returning from Argentina, he organized the service of Endemic Diseases Study, to coordinate a plan of medical and health research in several Brazilian states, promoting important research, especially on Malaria, Leishmaniasis and Chagas Disease.

[2] Evandro Chagas died in an air crash in Rio de Janeiro on November 8, 1940, aged 35.