[1] While its mechanism of action is not entirely clear, senna is thought to act by increasing fluid secretion within and contraction of the large intestine.

[1] Senna is used for episodic and chronic constipation though there is a lack of high-quality evidence to support its use for these purposes.

[12] Adverse effects are typically limited to gastrointestinal reactions and include abdominal pain or cramps, diarrhea, nausea, and vomiting.

[12] Regular use of senna products can lead to a characteristic brown pigmentation of the internal colonic wall seen on colonoscopy.

[17] Senna is an over-the-counter drug available in multiple formulations, including oral formations (liquid, tablet, granular) and rectal suppositories.

Senna products are manufactured by multiple generic drug makers and sold under various brand names.

[13] Ex-Lax, Geri-kot, Perdiem Overnight Relief, Senexon, Pursennid, Senna Smooth, Senna-Gen, Senna-GRX, Senna-Lax, Senna-Tabs, Senna-Time, SennaCon, Senno, Senokot.