Three new crewmembers (Scott Kelly, Alexander Kaleri and Oleg Skripochka) arrived aboard the ISS 10 October 2010 on Soyuz TMA-01M to join Douglas Wheelock, Fyodor Yurchikhin and Shannon Walker, and formed the full six member crew of Expedition 25.

On 2 November 2000, Expedition 1 commander William Shepherd and flight engineers Sergei Krikalev and Yuri Gidzenko became the first residents of the space station.

Progress M-08M spacecraft delivered about 2.5 tons of cargo supplies including water, air, fuel and hardware for the Russian Molniya-Gamma and Coulomb Crystal experiments to the station.

During station-keeping as part of the rendezvous operations, flight controllers in Moscow instructed cosmonaut Alexander Kaleri to activate the TORU manual docking equipment and take over the piloting tasks from the Progress' autonomous KURS system.

The switch to manual mode was decided at range of 194 m. Kaleri worked inside the space station's Zvezda module to fly Progress M-08M remotely using television views and a pair of joysticks and guided it to the successful docking.