FK1012 is a dimer consisting of two molecules of tacrolimus (FK506) linked via their vinyl groups.

[1] It is used as a research tool in chemically induced dimerization applications.

FK1012 is a chemical inducer of dimerization (CID) which makes the protein capable of dimerization or oligomerization of fusion proteins containing one or more FKBP12 domains.

[2] It is used in pharmacology to act as a mediator in the formation of FK506 dimer.

[3] FK506 binding proteins (FKBPs) do not normally form dimers but can be caused to dimerize in the presence of FK1012.