The episode featured guest performances by Seth Rogen, Meredith Baxter, Peter Chernin, Fred Savage, Daniel Stern, Ed Helms, Sharon Tay, John Moschitta, Jr. and Mark DeCarlo.

Rhonda Latimer, an aging reporter for Fox News who is idolized by viewers because of her good looks, is dismissed when the network's first high-definition broadcast exposes her wrinkles, leaving a job opportunity open.

The two decide to take the story into their own hands and confront who they expect to be Moore and a naked Limbaugh in the same bedroom, only to discover that both are personas portrayed by Fred Savage, who has created bodysuits of them and other public figures – including Tony Danza, Camryn Manheim, Malcolm Jamal Warner, Kevin Nealon, John Forsythe and Lars Ulrich – as a means of continuing his acting career.

Meanwhile, Peter, with help from Chris and Meg, decides to create an animated series about a trio of handicapped ducks entitled Handi-Quacks due to Lois' newfound connections with Fox.

He and Chris settle on developing the show's pilot episode around a joke involving a wood stove and a house of cards, and invite Cleveland, Quagmire and Joe to voice the characters.

[1] Then-Fox Entertainment Group CEO Peter Chernin and The Wonder Years star Fred Savage also guest-starred, along with Daniel Stern as that series' narrator, and Ed Helms, Sharon Tay, John Moschitta, Jr. and Mark DeCarlo appeared as well.

Recurring voice actors Jackson Douglas, Jennifer Tilly, and Kim Parks, and writers Kirker Butler, Steve Callaghan, Mark Hentemann, Danny Smith, Alec Sulkin, and John Viener made cameo appearances in the episode as well.

[7] Later on at the studio, Stewie's broadcast on Fox News is a parody of a viral video clip of an angry Bill O'Reilly misreading his teleprompter; this scene was cut from the TV airing due to profane language and time constraints, but is on the DVD version.

When Fred Savage is proven to be Rush Limbaugh and Michael Moore, he also reveals himself to be Tony Danza, Camryn Manheim, Malcolm-Jamal Warner, Kevin Nealon, John Forsythe, and Metallica drummer Lars Ulrich.

[7] After Savage confesses to his multiple identities, the voice-over from The Wonder Years (Daniel Stern reprising his role) is heard and Fred angrily shouts at him, "I don't need you anymore!"