The construction of the Faculty of Medicine was proposed in 1968 by Prof. Bimala Kalakicha to the council of Khon Kaen University.

[1] The proposal was passed on to the governmental cabinet and eventually made it into the 'Third National Economic and Social Development Plan' of 1972-1976.

In 1973, a proposal was made to the cabinet requesting for assistance from the government of New Zealand in the construction of the university hospital.

The construction of the university hospital was initiated in 1973, designed by the British company Llewelyn-Davies Weeks Forester-Walkers and Bor.

and construction by the New Zealand company Kingston Reynolds Thom & Allardice Limited (KRTA).