Other products, such as guar gum and maltodextrose, are "generally recognized as safe (GRAS)" by the FDA; this is also based on scientific testing and long-term consumption by a variety of consumer demographics.
[4][5] With excessive use, polydextrose can have a laxative effect, and olestra may cause loss of fat-soluble vitamins in the form of fatty stools and is liquid at body temperature.
[6] Esterified propoxylated glycerol (EPG), which is a solid at body temperature,[7] achieved GRAS status for confectionery uses in November, 2015.
EPG's GRAS status expanded to use at levels up to 38 percent by weight in baked goods and baking mixes, frozen dairy desserts and mixes, grain products and pasta, gravies and sauces, nuts and nut products, and soft candy.
[8] At this time, there is little supporting evidence to accompany claims that these, or other fat substitutes, are hazardous; however, more long-term research is needed.