Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea.

[1] Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.

[2] Febrifugine has antimalarial properties and the synthetic halogenated derivative halofuginone is used in veterinary medicine as a coccidiostat.

Other synthetic febrifugine derivatives have been used against malaria, cancer, fibrosis, and inflammatory disease.

[3]