Fenpropimorph

Fenpropimorph is a morpholine-derived fungicide used in agriculture, primarily on cereal crops such as wheat.

[1] It has been reported to disrupt eukaryotic sterol biosynthesis pathways, notably by inhibiting fungal Δ14 reductases.

[2] Although used in agriculture for pest management purposes,[1] it has been reported to have a strong adverse effect on sterol biosynthesis in higher-plants by inhibiting the cycloeucalenol-obtusifoliol isomerase.

[3] This inhibition was shown to not only alter the lipid composition of the plasma-membrane,[4] but also impact cell division and growth, in plants.

[5] In addition to its effects on fungi, fenpropimorph is also a very high affinity ligand of the mammalian sigma receptor.