De Regt began playing for Quick Boys '31 in southern Venlo.
[1] De Regt gained promotion to the Eredivisie in the 2006–07 season after beating RKC Waalwijk in play-offs.
[2] De Regt initially started as a right-back, but began starting as a regular centre back together with Frank van Kouwen due to injuries of centre backs Reekers and Verdellen.
In the 2012–13 season, De Regt plays on loan for Helmond Sport in the Eerste Divisie.
On 1 July 2019, De Regt returned to Helmond Sport on a one-year deal.