Fluazinam

[1] The mode of action involves the compound being an extremely potent uncoupler of oxidative phosphorylation in mitochondria[2] and also having high reactivity with thiols.

Because of its extensive usage to control late blight in Europe, there are confirmed reports of resistance to fluazinam appearing in P. infestans in genotypes EU_33_A2 and EU_37_A2.

[5] Fluazinam is also used to control Sclerotinia on peanuts and turf, Botrytis on grapes and beans and clubroot in brassicas.

[1] The acute oral median lethal dose in rats is very low at over 5000 mg/kg due to the compound's reactivity with thiols.

This reactivity can have negative consequences since repeated exposure can cause skin sensitization and dermatitis to develop in some individuals.