Born in Tirana, Albania, of Italian parents, Coluzzi soon moved to Italy with her family to Perugia.

Coluzzi declined the offer to continue her studies, but however the encounter with Fellini marked her life, and she eventually decided to leave the university to pursue a career in the cinema.

[2] She started her career as a body double, first of Mylène Demongeot in Fantômas and later of Marisa Mell in Danger: Diabolik.

[2] One year later she played Tarsilla Tettamanzi in Alberto Lattuada's Come Have Coffee with Us, and for this role she won a Nastro d'Argento for Best Supporting Actress[3] and a Globo d'oro in the same category.

[4] In the following years Coluzzi was mainly active in comedy films, especially in the commedia sexy all'italiana genre, often playing roles of unbearable and jealous wives.