After the election to the magistrate of the Twelve Offices in March 1685, his career made a qualitative leap, and in the same year he was in the shortlist of candidates for the French embassy, entering the College in November with the appointment as Wise Man of Terraferma, a position to which he was recalled ten times between 1685 and 1696.

From the first audience with the Emperor Leopold I of Habsburg, beyond the conventional manifestations of praise of the sovereign, he felt the rigidity of the counterpart on bilateral issues and the scarce propensity to conduct negotiations with the Turks in common agreement, resumed in the November 1698 in Carlowitz.

The long, dense and frequent dispatches sent to Venice, as well as the correspondence with Ruzzini, document Loredan's lucid awareness of the difficult Venetian position and of the fact that the compactness of the allies was not at all in effect.

[6] In the second part of his mandate, Loredan returned to routine, trying, with little success, to resolve bilateral issues and at the same time decipher the complex mechanisms of Habsburg power together with a careful reading of the international scenario.

The last dispatch was sent on 13 April, and on 5 May 1703, Loredan obtained permission to repatriate, after the troubled events of Carlowitz and the intense and painful activity carried out at the imperial court.

[4] On 5 June 1702, he was elevated to the prestigious position of Procurator of San Marco de Citra, to which he could add the title of Knight of the Golden Spur, conferred on him by the emperor on his leave.

[4] He remained unmarried, and left a very respectable inheritance, increased over the years, despite the huge expenses incurred for the embassy, and consisting of properties in Venice and vast land holdings, embellished with prestigious manor houses, in the Venetian area, around Treviso and Padua, in the Veronese area and in the territories of Rovigo and Polesine, to his brother, Giovanni, also unmarried, and to his nephews, children of his brother Andrea.